Rapidly receive sections as slim or thick as your application needs, without having worrying about losing or distorting important tissue samples.
Our convert-vital SmartBatch+ technique combines electrophoretic tissue clearing and immunolabeling into a person substantial-throughput device.
Antibodies may perhaps get months to diffuse by means of only some millimeters of tissue, using a steep labeling gradient from floor to core.
Managing the CLI straight from a Gradle activity will not be presently supported. A distribution have to be created by way of gradlew :j2d-cli:distZip to produce a zip file made up of everything necessary to operate.
SE uses a rotational electrical subject to disperse really electromobile molecules (which include antibodies or surfactant micelles) all through a porous sample with no harming electrically charged structures inside the tissue. This enables 2-4 working day clearing of intact organs,
Our preformulated EasyIndex Option raises and homogenize the refractive index of delipidated tissue samples, rendering them absolutely clear. This allows mild penetration in the sample and makes sure the acquisition of superior-resolution, in-focus image information.
Megatome can be a novel microtome which allows for top-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue damage and knowledge reduction.
It’s time to enhance your microtome to Megatome. With precise superior-frequency slicing for an unmatched number of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous purposes.
The SmartSPIM gentle sheet microscope offers unparalleled resolution and acquisition velocity through intact tissue volumes, although its modular design means that you can update and customize particular person elements.
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Protect avoids the variability of hydrogel embedding and the information reduction from PFA preservation, shielding specimens for many rounds of processing.
Leverage the Clear+ tissue clearing system, in addition to eFLASH and patented stochastic electrotransport technologies, to fast obvious and label whole organs. Critical highlights and functions include:
Our novel Defend tissue preservation method sorts intramolecular bonds employing polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.